So I finally figured this out on my own and thought I would post as an FYI. With all the Microsoft OS updates and security changes to guard against malware and other cyber intrusion, something changed on my laptop with the latest install of Windows 10 update version 1903. It wasn't that the directory for BS3 had moved, Windows security was not letting the BS3 executable access the folder where all the files live. Changes will need to be made in Windows Security and here are the steps to correct:
1. Access Windows 10 Settings from the main icon
2. Select Windows Security
3. From the left side menu bar, select Virus & threat protection
4. Scroll down to Ransomware protection and select "Manage ransomware protection". Once inside that window, you should see that "Controlled folder access" is more than likely turned "on". Assuming it's on, you will see three sub links: "Block history", "Protected Folders" and "Allow an app through Controlled folder access".
5. Click on "Allow and app through Controlled folder access" and it should take you to another screen with that heading. Click on "Add an allowed app" and view Recently blocked Apps.
6. The Recently blocked apps pop-up should indicated that BeerSmith3.exe (or BeerSmith2.exe) are being blocked. Simply click the "+" button and add one or both of the executable files to grant folder permission. Once you have added them you're pretty much done.
7. Close out of everything and restart the BS3 (or 2) application and things should work.
I took some screen captures but it's too much to include with this posting. Hopefully the directions are clear enough. Best of luck and have a great brewing day!